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<pre>Array ( [var] => cut_url ) </pre> Resume for Vinay Kumar S. for Researcher / Scientist / Biotechnology & Pharmaceuticals in Daejeon, Korea, (South) Republic of. Search More Resumes for Researcher / Scientist on Resumark.com #2EED7PVUW
 

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Resume for Vinay Kumar S. for Researcher / Scientist / Biotechnology & Pharmaceuticals in Daejeon, Korea, (South) Republic of




Occupation: Researcher / Scientist Industry: Biotechnology & Pharmaceuticals
Country: Korea, (South) Republic of City: Daejeon
State: Taejon-jikhalsi ZIP: 305764



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Vinay kumar S. Mobile: Email : OBJECTIVE AND SUMMARY A highly motivated researcher armed up with full set of drug discovery and development Medicinal Chemistry skills, solid analytical abilities, resultdriven mindset and cando spirit. Being an excellent team player with selfdiscipline, outstanding communication skills and global experience currently looking for a challenging and interesting role of a Senior Scientist Medicinal Chemistry in MNC PERSONAL DATA Date of Birth . Current Address Department of Medicinal Chemistry, College of Pharmacy, Chungnam National University Daejeon , South Korea QUALIFICATION * years of work experience in drug discovery projects based on various targets such as anticancer, inflammation and melanogenesis in pharmaceutical industry and academic research. * Excellent teamwork, interpersonal and presentation skills. * Doctorate in Medicinal Chemistry/Synthetic Organic Chemistry. * Strong drug discovery project management skills; adapt at operating budget restriction and time constrains of pharmaceutical industry. * Well organized, trained, selfmotivated and ambitious. * Excellent planning, analysis, negotiation, troubleshooting and reporting skills. SUMMARY OF EXPERIENCE Nov. ~ Present Department of Medicinal Chemistry, College of Pharmacy, Chungnam National University, Daejeon, South Korea. Postdoctoral Scientist March ~ July Aurigene Discovery Technologies Ltd., Bangalore, India Associate Scientist in New Drug DiscoveryMedicinal Chemistry Jan. ~ Feb. Orchid Research Laboratories Limited, Chennai, India Research Scientist in New Drug discoveryMedicinal Chemistry May ~ March Kyoto Pharmaceutical University, Kyoto, Japan Post Doctoral Fellow Medicinal Chemistry April ~ April Department of Medicinal Chemistry, College of Pharmacy, Chungnam National University, South Korea Post Doctoral Fellow Medicinal Chemistry Nov. ~ Feb. Biochemistry Laboratory, Dept. of Biology, Kongju National University, South Korea Research Fellow EDUCATIONAL QUALIFICATION Sep. ~ Nov. Doctorate in Synthetic Organic Chemistry from Indian Institute of Technology IIT, Roorkee, Roorkee, India. Title of thesis: "Synthesis, Biological Evaluation and Analytical Studies of some Heterocyclic Compounds" Aug. ~ July. Master of Philosophy in Applied Chemistry, from Indian Institute of Technology IIT, Roorkee, Roorkee, India . July ~ July Master of Science in Applied Chemistry from Gurukul Kangari University, Haridwar, India . AWARDS * Awarded Postdoctoral Fellowship by National Research Foundation Korea under Priority Research center program at Institute of Drug Research & Development, College of Pharmcy, CNU, Korea Tiill date * Performance recognition award for achieving milestone in the project, Aurigene Discovery Technologies Limited, Bangalore, India. * Awarded COE Postdoctoral Fellowship under "The st Century COE Program" of the Ministry of Education, Culture, Sports, Science and Technology of Japan. * Awarded Senior Research Fellowship by Council of Scientific and Industrial Research CSIR, New Delhi, India ADDITIONAL REMARKS * Research Skill * Methods/ Techniques ▪ Multistep chemical synthesis of novel modified heterocyclic compounds. ▪ Multistep solution phase peptide or peptidomimetics synthesis. ▪ Multigram scaleup of developed synthetic protocols. ▪ Designing and synthesis of enzyme inhibitors. ▪ Chromatographic purification of heterocycles and peptides. ▪ Spectrometric determination of chemical structure based on NMR H, C, and mass spectral data FAB, ES, MALDI. * Instrumentation/Equipments ▪ Experience of operating the JEOL AL MHz and Varian MHz NMR in structure identification. ▪ Experience of Molecular modeling & Drug designing using MOE and Hyperchem. ▪ Extensive experience with different liquid chromatographic techniques with silica gel for smallscale purification. ▪ Experience of operating the PerkinElmer Jasco Report IR spectrometer collected again peak at cm of polystyrene in functional group characterization. * Computer skills MS Office, ChemBioOffice, MOE, Hyperchem SCIENTIFIC PUBLICATIONS * Importance of Imidazolidinone Motif in Phenyl Narylsulfonylimidazolidinone for their Anticancer Activity. Bulletin of the Korean Chemical Society KCS Publication, , Accepted for publication. * Effect of the isosteric replacement of the phenyl motif with furyl or thienyl of phenylNarylsulfonylimidazolones as broad and potent anticancer agents. Med. Chem. Commun. RSC Publication, , Advance Article DOI: ./CMDD, Concise Article. * Structureactivity relationship studies of novel arylsulfonylimidazolidinones for their anticancer activity. European Journal of Medicinal Chemistry Elsevier Science Publication, , , . * Ketonethiosemicarbazones: StructureActivity Relationships for their Melanogenesis Inhibition. . Bioorganic & Medicinal Chemistry Letters Elsevier Science Publication, , , . * Structural requirements of Ebenzylideneamethyl,a,,,,hexahydronaphthalenHone derivatives as novel melanogenesis inhibitors. Bioorganic & Medicinal Chemistry Letters Elsevier Science Publication, , , . * Structural characteristics of thiosemicarbazones as inhibitors of melanogenesis. Bioorganic & Medicinal Chemistry Letters Elsevier Science Publication, , , . * Design and synthesis of novel hydroxyalkylaminomethylchromones for their IL inhibitory activity. Bioorganic & Medicinal Chemistry Elsevier Science Publication, , , . * The scope of thallium nitrate oxidative cyclization of chalcones; synthesis and evaluation of isoflavone and aurone analogs for their inhibitory activity against interleukin. Bioorganic & Medicinal Chemistry Elsevier Science Publication, , , . * Refinement of the pharmacophore of ,dihydroquinazolineHthiones for their antimelanogenesis activity. Bioorganic & Medicinal Chemistry Letters Elsevier Science Publication , , . * Structural requirements of Nphenylthioureas and benzaldehyde thiosemicarbazones as inhibitors of melanogenesis in melanoma B cells. Bioorganic & Medicinal Chemistry Letter Elsevier Science Publications, , , . * Novel Benzo[d]imidazoleHthiones as Potent Inhibitors of the αMSH induced Melanogenesis in Melanoma B Cells. Chemical and Pharmaceutical Bulletin The Pharmaceutical Society of Japan publication, , , . * Synthesis and evaluation of novel chromone analogs for their inhibitory activity against interleukin. European Journal of Medicinal Chemistry Elsevier Science Publication, , , . Impact factor . * Synthesis of Glutamic acid and Glutamine peptides possessing a Trifluoromethyl Ketone Group as SARS CoV CL protease inhibitors. Tetrahedron Elsevier Science Publication, , , . * Screening of some medicinal plants for antilipase activity, Journal of Ethnopharmacology Elsevier Science Publication, , , . * In vitro AntiTyrosinase Activity of Hydroxymethylfurfural isolated from Dictophora indusiata, Phytotherapy Research John Wiley & Sons Ltd. Publication, , , . * Mushroom Tyrosinase: Recent Prospects, Journal of Agricultural and Food Chemistry ACS Publication, , , . * Synthesis, characterization and Hg II ion selectivity of nitromethylphenylmethylmethoxy,,,tetrahydropyrimidineHthioneTPT, Electroanalysis WILEYVCH Verlag GmbH publication, , No., , . * AntiHIV, antibacterial and antifungal activities evaluation of a variety of heterocyclic compounds containing N and/ or Sulfur, Indian J. Pharma. Sci. IPA publication, , , . * Synthesis and antiinflammatory activity evaluation of some acridinylaminoantipyrine, acridinylaminoanthraquinone, acridinothiourea and thiazolinothiourea derivatives. Phosphorous, sulfur and silicon Taylor & Francis Publication, UK, , , . * Synthesis, antiinflammatory and analgesic activity evaluation of some mercapto pyrimidine and pyrimidobenzimidazole derivatives. Synthesis Thieme Verlag Publication, Germany, No. , , . Impact factor . * Synthesis and antiHIV screening of some heterocyclic compounds, Phosphorus, sulfur and silicon Taylor & Francis Publication, UK, , , . * Antiinflammatory and analgesic activity evaluation of heterocyclic compounds, synthesized by the reaction of isothiocyanatomethylpentanone with amines, Phosphorous sulfur and silicon Taylor & Francis Publication, UK, , , . * Analysis of some Ayurvedic Bhasmas. Indian Drugs, , , . REFERENCES WILL BE FURNISHED UPON REQUEST . Dr. SangHun Jung, College of Pharmacy, Chungnam National University Korea . Dr.Yoshio Hayashi, Deptt. of Medicinal Chem., Tokyo Univ. of Pharmacy and Life sci., Japan . Dr. SungYum Seo, Department of Biology, Kongju National University Korea . Dr. A.K. Jain, Deptt. of Chem. Indian Institute of Technology,Roorkee IITR India DETAILED EXPERIENCE Nov. ~ Present Department of Medicinal Chemistry, College of Pharmacy, Chungnam National University, Daejeon, South Korea. Postdoctoral Scientist * As a Senior Researcher in our group, I am involved in various prospects of drug discovery & development with special concern on medicinal chemistry point of view. The projects on which I am currently concentrating are based on various targets such as anticancer, inflammation and melanogenesis and my job profile includes * Guiding the doctorate degree students in designing suitable target molecules and synthetic schemes. * Writing the research articles with understanding of structure activity relationship between molecules and their targets on medicinal chemistry for various international Journals. * Discussion on various prospects of medicinal chemistry within the group. March ~ July Aurigene Discovery Technologies Ltd., Bangalore, India Associate Scientist in New Drug DiscoveryMedicinal Chemistry * As a Lab Leader I was involved with drug discovery project based on anticancer Target with special focus on designing & synthesis of kinase inhibitors and my job profile included * Managing the group of scientists, * Designing the synthetic schemes of new scaffolds and implementation of them for the synthesis of NCE&;s. * Discussion with collaborators on various prospects of drug discovery and development * Interdepartmental such as molecular biology, SBDD structure based drug design, Pharmacology and analytical chemistry discussions on various aspects of drug discovery and development. Jan. ~ Feb. Orchid Research Laboratories Limited, Chennai, India Research Scientist in New Drug discoveryMedicinal Chemistry * As a Scientist I was involved with drug discovery project based on antibiotic Target with special focus on the PDF inhibitors.and my job profile included * Managing the group of scientists, * Designing & Synthesis of various peptidomimetics derivatives * Designing the synthetic schemes of new scaffolds and implementation of them for the synthesis of NCE&;s. * Interdepartmental such as molecular biology, SBDD structure based drug design, Pharmacology, analytical chemistry discussions on drug discovery and development. May ~ March Kyoto Pharmaceutical University, Kyoto, Japan Post Doctoral Fellow Medicinal Chemistry * Our group was involved in medicinal chemistry research based on molecular recognition. The main research targets were developing antimicrobial, anticancer drugs and enzyme inhibitors. Our research was focused on i biologically active peptides and their receptors, and ii proteases and their substrates. We studied the molecular recognition of these important compounds, and carried out designing and synthesis of peptidomimetic biological response modifiers. As a COE Postdoctoral Fellow I worked on a drug discovery project based on Human coronaviruses HCoVs with special focus on severe acute respiratory syndrome SARS. By working on this project I was able to design novel inhibitors for SARS which will be immensely helpful in the treatment of this disease and my job profile included * Synthesis and Evaluation of SARS Severe Acute Respiratory Syndrome Corona Virus CL Proteinase Inhibitors. * Designing the synthetic schemes of new scaffolds and implementing them for the synthesis of NCE&;s. * Discussion on various aspects of medicinal chemistry within the group. April ~ April Department of Medicinal Chemistry, College of Pharmacy, Chungnam National University, South Korea Post Doctoral Fellow Medicinal Chemistry * Our group was engaged in the designing and synthesis of various drug molecules. My research was focused on "Design & Synthesis of novel quinoline derivatives for their caspase inhibitory activity". My job profile included * Designing & Synthesis of caspase inhibitors. * Designing the synthetic schemes of new scaffolds and implementing them for the synthesis of NCE&;s. * Discussion on various prospects of medicinal chemistry within the group. Nov. ~ Feb. Biochemistry Laboratory, Dept. of Biology, Kongju National University, South Korea Research Fellow * Our group was searching for biologically active natural products, which had potential application as skin whitening and obesity reducing agents. Of particular interest to us were plant sources that have been used as foods or traditional medicines. My job profile included * A number of bioactive natural products had been isolated * Systematic study of the inhibition of tyrosinase and pancreatic lipase will lead to further understanding of its mechanism and identify potential inhibitors for practical applications. * Discussion on various aspects of biochemistry within the group.

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