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<pre>Array ( [var] => cut_url ) </pre> Resume for Neeraj S. for Researcher / Scientist / Biotechnology & Pharmaceuticals in Birmingham, Alabama. Search More Resumes for Researcher / Scientist on #Q7GDYKLMI

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Resume for Neeraj S. for Researcher / Scientist / Biotechnology & Pharmaceuticals in Birmingham, Alabama

Occupation: Researcher / Scientist Industry: Biotechnology & Pharmaceuticals
Country: United States City: Birmingham
State: Alabama ZIP: 35209

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Neeraj S., PhD Cell and Molecular Biology
| Beacon Crest Circle | Ph: |
|Birmingham, AL | |
| | |
• Highly motivated cell biologist with + years of research experience
• Highly competent in generating quality data in a teamoriented environment
• Experience with collaborative science, and the potential to organize and lead a productive
research team
• Excellent oral and scientific writing, intrapersonal and organizational skills
• PhD, Cell Biology Cilia and Microtubules /
Dept. of Cell Biology, University of Georgia, Athens, GA
Thesis: Significance and Regulation of Microtubulesevering in vivo
• M. S. Biotechnology Protein Folding, ProteinLigand Binding /
Dept. of Biotechnology, Aligarh University, Aligarh, UP, India
Thesis: Use of domain specific ligands to study ureainduced unfolding of bovine serum
• Summer Internship as part of MS program: Protein Purification
Indian Institute of Technology, New Delhi, India
• B. Sc. Biochemistry Hons /
Dept. of Biochemistry, Delhi University, New Delhi, India
Postdoctoral Research Fellow: Dept. of Cell Biology, / to
Univ. of Alabama at Birmingham, Birmingham, AL, USA
Project Title: Functional analysis of primary cilia and microtubules in chronic kidney disease
• Assessed the role of primary cilia in chronic kidney disease
• Investigated the effect of pharmacological drugs upon primary cilia length and microtubules
• Developed and validated novel cellbased and in vitro biochemical assays
• Identified biomarkers for chronic kidney disease induction and progression
• Discovered new paradigm in polycystic kidney disease development
• Evaluated and recommended new procedures and techniques to the research group
Graduate Student Researcher: Dept. of Cellular Biology, / to
University of Georiga, Athens, GA, USA
Thesis Title: In vivo analysis of microtubulesevering proteins in motile cilia assembly
• Established a first connection between microtubule dynamics and cilia assembly
• Documented novel ultrastructural phenotypes by using confocal microscopy and electron
• Executed gene expression and knockout studies to analyzed the function of ciliary
• Discovered functional link between katanin and tubulin posttranslational modifications
• Achieved recognition by "faculty of " recommended and highly cited cover page article in
"The Journal of Cell Biology"
• Mammalian Cell Culture: Transfection, Lentivirus mediated infection, stable cell line
development, clone selection, immunocytochemistry
• Molecular Biology: Plasmid vector construction using regular and gateway cloning,
Recombinant DNA technology, gene manipulation and gene expression, PCR, RTPCR,
• Biochemistry: Protein expression and purification GST and Histagged, Subcellular
fractionation, SDSPAGE, Western blotting
• Microscopy: Confocal Scanning and Spinning Disk, Transmission, Immunoelectron and
Scanning electron microscopy, Image analysis Metamorph, Volocity
• Computer proficiency: PC/MAC, Adobe Photoshop, MSOffice Excel, Word, PowerPoint
Endnote, GraphPad Prism, Vector NTI, Sequence alignment
• S. N, et al. Soluble levels of cytosolic tubulin regulate ciliary length control. Molecular
Biology of the Cell. Jan .
• Neeraj S. and Bradley K. Yoder. Loss of primary cilium affects microtubule acetylation.
• Nicolas F. Berbari, Nicolas W. Kin, Neeraj S., Ed Michaud, John F. Kearney and
Bradley K. Yoder. Trafipmutant mice display phenotypes of primary cilia
mutants. Submitted
• Dragos Olteanu, Xiaofen Liu, Wen Liu, Venus Roper, Neeraj S., Bradley Yoder, Lisa
Satlin, Erik Schwiebert, and Mark Bevensee. Increased Na+H+ Exchanger Activity on the
Apical Surface of a Ciliumdeficient Cortical Collecting Duct Principal Cell Model of Polycystic
Kidney Disease. Submitted
• Nathan E. Hellman, Yan Liu, David R. Beier, Christopher Ward, Zhaoxia Sun, Neeraj
S., Bradley K. Yoder, and Iain A. Drummond. foxja regulates cilia function in response
to injury and cystic kidney disease. Proc Natl Acad Sci U S A. Oct ;:
• Neeraj S., et al. Role of primary cilia, proliferation and kidney injury in development of
polycystic kidney disease. Manuscript in preparation.
• Drashti Dave, Neeraj S., Dorota Wloga and Jacek Gaertig. DYF is required for
assembly of the axoneme in Tetrahymena. Eukaryotic Cell. Sep;:.
• Dorota Wloga, Krzysztof Rogowski, Neeraj S., MarieHelene Br‰, Nicolette Levilliers,
Juliette Van Dijk, Carsten Janke, Bernard Edd‰, Kathleen Clark, Martin A. Gorovsky, Maria
JerkaDziadosz, and Jacek Gaertig. Glutamylation on alphatubulin is not essential but affects
the assembly and functions of a subset of microtubules in Tetrahymena. Eukaryotic Cell.
• Neeraj S., eta al. Ciliary dysfunction in developmental abnormalities and
diseases. Invited Review for Book series: Current Topics in Developmental Biology
‘Ciliary function in mammalian development’. ; :
• Neeraj S., et al. Katanin Regulates Dynamics of Microtubules and Assembly of Cilia.
The Journal of Cell Biology, Vol. , No. , – Cover page article
• Saad Tayyab, Neeraj S., Mushahid K M. Use of domain specific ligands to study urea
induced unfolding of bovine serum albumin. Biochem. Biophys. Res. Comm. :
• FASEB, Biology of Cilia and Flagella, Annual Meeting, Saxtons River, Vermont July
• Soluble levels of cytosolic tubulin regulate ciliary length control. American Society for Cell
Biology, Philadelphia, PA Dec
• Primary cilia and fluidflow coordinately establish the orientation of mitotic spindle orientation.
National Kidney Foundation Spring Clinical Meeting, Orlando, FL April
• Temporal analysis of primary cilia in pathogenesis of polycystic kidney disease. American
Society for Cell Biology, th Annual meeting, San Diego, CA Dec
• Primary cilia regulate the orientation of mitotic spindles. American Society for Cell Biology,
San Francisco, Dec
• Katanin is required for the assembly of motile cilia, th American Society for Cell Biology
Annual Conference, San Diego, CA Dec
• Travel award, National Kidney Foundation to attend National Kidney Foundation, Clinical
Spring meeting. April
• Postdoctoral Research Fellowship: National Kidney Foundation.
• Travel award: office of postdoctoral education, University of Alabama at Birmingham to attend American
Society for Cell Biology, annual conference, December
• Travel award, th American Society for Cell Biology Annual Conference, San Diego,
• American Society for Cell Biology ASCB
• Society for Developmental Biology SDB
• Volunteered as a judge for Altamont high school science research competition Birmingham,
• Acted as a reviewer for Graduate Student Research Day at Univ. of Alabama at Birmingham
• Served as a judge for Minority Affairs Committee research session at ASCB annual meeting
• Peerreviewer for scientific journals Laboratory investigation, Journal of American Society for Nephrology, Cell
Biology International, Biology of the Cell and many more
• Advised and mentored more than science major undergraduate students at the Univ. of
EMPLOYMENT STATUS: Employment authorization for any employer in United States

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